Sami-Sabinsa reveals new finding on curcumin C3 complex

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To study its effect combined with BioPerine®, on serum cytokine concentrations

In a recently published clinical trial findings, researchers studied the effects of the administration of Bengaluru based Sami-Sabinsa Group’s Curcumin C3 Complex with BioPerine in combination on the levels of the cytokines leptin and adiponectin in critically ill patients with traumatic brain injury (TBI).

Sixty-two patients were given 500 mg C3 Complex and 5 mg BioPerine as supplementation daily. A significant decrease was noted in the pro-inflammatory cytokine leptin in the treatment group compared with the placebo group. While leptin is often associated with food intake and energy expenditure, its importance in aging conditions, serious illness, and stressful injuries is increasingly recognized.

Simultaneously the researchers also monitored the levels of the beneficial anti-inflammatory cytokine adiponectin. They commented that the increase in adiponectin did not reach statistical significance, presumably due to the short 7-day duration of this trial. They also pointed to other trial results in which longer durations of curcuminoids administration resulted in adiponectin level increases.

Sami-Sabinsa Group Founder and Chairman Dr. Muhammed Majeed revealed that he was happy with the utility of C3 Complex with BioPerine in controlling the expression of cytokines in TBI patients and that only benefits and no adverse effects had materialized.

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