CURCUGEN, DolCas Biotech’s bioavailability-enhanced, water-dispersible curcuminoid complex, has received Self-Affirmed Generally Recognized a s Safe (GRAS) status.
This designation was unanimously accorded by an independent panel of scientific experts and based on scientific procedures, concluding that CURCUGEN meets FDA’s definition of safety when used as an ingredient in yogurt, nutrition bars, smoothies, and other food and beverage products at levels of 40-60 mg per serving.
The panel concurrently determined an Acceptable Daily Intake (ADI) of CURCUGEN at 210 mg/person/day, using both JECFA standards and which falls in line with the 2010 EFSA scientific opinion on the “conservative estimate” for assessing exposure to curcumin.
The committee also determined an upper limit up to 1400 mg/person/day in the same food formats which it considered was safe and meet the requirements of GRAS, as defined by the FDA. This conclusion was drawn directly from a battery of toxicological studies performed using CURCUGEN.
Next-gen qualities DolCas’ new curcumin formula is a 100% natural, water-dispersible curcumin ingredient. It is a proprietary 98.5% turmeric-based preparation of turmeric oleoresin extract and fresh turmeric rhizome extract derived from Curcuma longa L. The company applies a SELF D platform technology to optimize the oleoresin base so that its benefits can be fully realized.
CURCUGEN’s 98.5% turmeric formulation provides a high concentration of curcuminoids at a 50% standard, without omitting other, well-characterized and functional turmeric actives, including turmeric essential oils and polysaccharides.
DolCas will take the brand to the highest level of safety appraisal with the FDA in a comprehensive GRAS submission within the next few months.