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A team of scientists from the CSIR-Central Food Technological Research Institute (CFTRI), Mysore, has found out the mechanism by which fenugreek and onion protect heart-related disorders in diabetic patients.
Previously, it was known that higher production of an enzyme (angiotensin-converting enzyme or ACE) and receptor (AT1 of renin-angiotensin system) in the cardiac tissue of diabetic patients is a cause of heart-related disorders. Scientists have shown that both the enzyme and receptor are produced to a lesser degree in mice supplemented with fenugreek and onion and, therefore, the entire successive biochemical pathway initiated by these two is attenuated.
Although fenugreek and onion individually were able to ameliorate heart-related disorders in diabetic rats, it was found that they worked better in combination.