IISER Bhopal sequences genome of medicinal herb Giloy as a first

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The genome sequence of Giloy could be a breakthrough as the potential therapeutic agent for diseases like COVID-19 in the future

The Indian Institute of Science Education and Research (IISER) Bhopal scientists have sequenced the genome of Giloy (Tinospora cordifolia), a plant with medicinal properties, for the first time in the world.

The genome and transcriptome sequencing of Giloy is important due to its tremendous use in pharmaceuticals and ayurvedic formulations to treat various health conditions including COVID-19 and can provide deep insights into the genomic basis of its medicinal properties.

The usage of Giloy is also recommended under Ayurveda practice by the Ministry of AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy) and the Ministry of Health and Family Welfare, Government of India, in prophylactic care as well as therapeutic applications for all symptomatic or asymptomatic patients infected with COVID-19. It is also used in fever and diabetes.

Elaborating the highlights of this Research, Dr. Vineet K. Sharma, Associate Professor, Department of Biological Sciences, IISER Bhopal, said, “Giloy also has anti-microbial activity and is used in skin diseases, urinary tract infection, and dental plaque, among others. It is also found to reduce the clinical symptoms in HIV-positive patients and its antioxidant activity has anti-cancer and chemo-protective properties. Giloy extracts are found to be potential candidates in treating various cancers like brain tumour, breast cancer, and oral cancer, as well.”

 

Image caption- The research team was led by Dr. Vineet K. Sharma, Associate Professor, Department of Biological Sciences, IISER Bhopal, and comprised Shruti Mahajan and Abhisek Chakraborty, PhD Students, IISER Bhopal

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