Study says curcumin extract can fight common neurodegenerative disorders


BCM-95 turmeric extract and purified essential oil of turmeric demonstrates new capabilities

A new study has recently revealed a neuroprotective effect of curcumin extract in combination with its essential oil, suggesting a nutraceutical solution for mitigating the toxic effects of aluminum build-up in the brain. In the study, Kerala based Arjuna Natural Pvt., Ltd.’s BCM-95 turmeric extract and purified essential oil of turmeric demonstrated new capabilities in preventing neurotoxicity resulting from aluminum exposure.

The presence of free curcumin and its metabolites were observed in the brain and plasma secondary to the complex’s superior bioavailability capabilities. These findings present positive implications for harnessing this unique curcumin delivery system to alleviate a range of common neurodegenerative diseases. Research has suggested that brain health can be compromised by exposure to neurotoxins, with aluminum believed to be of particular concern.

Chronic exposure can actuate a neuroinflammatory response and rouse a state of oxidative stress, raising risks for neural damage. It has been implicated in a number of neurodegenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. High concentrations of aluminum have been found to increase amyloid aggregation and deposition in neuronal tissues — a key feature of Alzheimer’s Disease.

The study of curcumin extract in combination with its essential oil was conducted at the Department of Clinical Pharmacy, Jazan University, in Saudi Arabia and the Nalanda College of Pharmacy, Nalgonda, India.

The research evaluated the exposure of aluminum in experimental models at different doses comparing Bioavailable curcumin and turmeric extract. This bioavailable turmeric extract complex also demonstrated abilities to prevent neurotoxicity significantly better than standard turmeric extracts.


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