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Hyderabad-based Zeus Hygia Lifesciences, a leader in nutraceutical solutions, has recently unveiled Metaberine,a green-process enriched berberine. It has been developed using their proprietary BioSOLVE Technology. Dr Arunkanth Krishnakumar, Co-founder and CEO, Zeus Hygia, reveals more about the nutraceutical industry, the BioSOLVE Technology and plans for India and global markets
What is the future of the nutraceutical industry in India?
The future of India’s nutraceutical industry is extremely promising. Rising health consciousness, an increase in lifestyle-related disorders, and the growth of the middle class are driving strong demand for preventive and wellness-focused solutions. India is well-positioned to be a global leader in nutraceutical innovation, thanks to its rich biodiversity, deep traditional knowledge of botanicals, and increasing focus on clinical validation. Segments such as metabolic health, cognitive support, immunity, and healthy aging are expected to witness accelerated growth.
Nutraceuticals are regulated under the Food Safety and Standards Act of 2006 by FSSAI. Did you face any regulatory challenges while launching Metaberine in India?
Launching Metaberine in India required rigorous compliance with FSSAI regulations. We prepared and submitted extensive technical and quality documentation to ensure adherence to standards. While the process was meticulous, it ultimately strengthened the product’s credibility and market acceptance.
Do you think stricter regulations could enhance trust both among domestic and global consumers?
Absolutely. Strong, science-backed regulations raise the bar for the entire industry by filtering out substandard products and building consumer trust. A well-defined regulatory framework encourages manufacturers to invest in research, clinical validation, and transparent labeling. This not only safeguards public health but also makes Indian nutraceuticals more competitive globally, where evidence-backed, high-quality products are increasingly in demand.
How easy/difficult is it to source ingredients like berberine in India?
Berberine is naturally present in Berberis aristata, a plant native to northern India and the Himalayan regions, making it reasonably accessible. The challenge, however, lies not in sourcing the raw material but in converting it into high-bioavailability, clinically effective formulations. Conventional extracts suffer from poor absorption and require high dosages. That’s why our focus is on advanced processing technologies to unlock the full therapeutic potential of locally sourced ingredients.
Tell us more about the BioSOLVE Technology used to process berberine and launch Metaberine.
BioSOLVE Technology is our proprietary formulation platform designed to address the inherent limitations of standard herbal extracts like berberine. It enhances solubility, improves absorption, and provides controlled release of the active ingredient. By boosting bioavailability, BioSOLVE enables lower dosages, faster onset, sustained effects, and reduced gastrointestinal side effects. This results in a more consistent and reliable consumer experience—backed by robust clinical data.
How much did you invest in R&D before launching Metaberine?
We made significant investments in R&D before launching Metaberine. This included preclinical studies, clinical trials, development of the BioSOLVE technology, quality validation, and regulatory compliance. Our deep commitment to research ensures that Metaberine is not just another market offering but a scientifically validated solution for metabolic health.
What kind of quality tests did you conduct before the launch of Metaberine?
Metaberine underwent a rigorous battery of quality and safety tests before its launch. These included raw material identity and purity verification, microbial contamination analysis, testing for heavy metals and pesticide residues, and stability studies to determine shelf life. In addition, bioavailability studies were conducted and benchmarked against conventional berberine, along with clinical proof-of-concept studies to validate both safety and efficacy. All tests were performed in accordance with globally recognised standards, ensuring reproducibility, reliability, and the highest levels of consumer safety.
What are your plans for India and the global market five years down the line? Do you have new products in the pipeline?
Over the next five years, our strategy is to expand Metaberine globally, positioning it as a flagship solution for metabolic health supported by continued clinical research and real-world evidence. Simultaneously, we are building a diverse product pipeline targeting some of the most relevant health segments today, including healthy aging, prostate health, eye health, sexual wellness, and digestive health. Our vision is to pioneer science-led, next-generation nutraceuticals that not only address current health challenges but also promote long-term holistic well-being on a global scale.
Sanjiv Das
sanjiv.das@mmactiv.com