Lubrizol’s microencapsulated iron outperforms in absorption and gut tolerance

​Gentle on the stomach, Lipofer micronized microencapsulated iron reverses iron deficiency within 14 days

New research confirms the exceptional performance of Lubrizol’s microencapsulated iron ingredient Lipofer in comparison to traditional iron sources. The in vivo study, which evaluated iron bioavailability and gastrointestinal tolerability in iron-deficient rats, found that Lubrizol’s proprietary formulation significantly outperformed conventional options, such as ferrous sulfate, ferrous bisglycinate, and other encapsulated iron salts.

Lubrizol’s orosoluble iron is a highly concentrated, micronized, and microencapsulated iron source designed specifically to reduce the associated side effects of iron supplementation while delivering a fully absorbable mineral that is significantly easier and pleasant to digest.

Lipofer microcapsules also contain lecithin, which helps the body absorb nutrients more effectively by integrating with the fats in cell membranes. Additionally, the tiny iron particles in Lipofer have a larger surface area, which enhances absorption and enables the iron to reach the intestine without causing side effects.

The Lipofer study, published July, 2025 in the peer-reviewed journal Nature, in, was an animal study designed and led by Roger Marineé-Casadó and revealed the ingredient’s high level of effectiveness in reversing iron deficiency anaemia within 14 days, while also being gentle on the stomach, as measured by markers of gastrointestinal side effects.

“The microencapsulation matrix we’ve developed ensures that iron is delivered in a controlled manner,” explains Isabel Gómez, Global Marketing Manager for Lubrizol Nutraceuticals. “This not only improves tolerability but also enhances the bioavailability of the mineral, as confirmed by the study’s haematological and biochemical markers. This study reinforces our commitment to developing science-driven, consumer-preferred solutions that address real nutritional challenges. Iron deficiency continues to affect billions globally, and our microencapsulated iron ingredient offers a breakthrough in both efficacy and comfort.”