The DINI AXIS research initiative is categorised into four steps
Mumbai based startup Esperer Onco Nutrition (EON), a pioneer in bringing comprehensive nutritional portfolio to oncology, has announced an important initiative to unlock influence of nutrition on immunity.
A team of scientists at EON have come up with an extensive research plan which collectively gives convincing evidence of the relationship between Diet Infections Nutrition Immunity and non-communicable diseases (NCDs) which the company has decided to persuade as the “DINI AXIS” concept to execute its research work.
The world has witnessed a rapid rise in nutrition-related disorders such as obesity, a risk factor for many of the non-communicable disease (NCDs) such as type 2 diabetes, coronary heart disease, stroke, hypertension, dental disease, osteoporosis, and some forms of cancer all over the world.
Talking about the initiative Mr. Raktim Chattopadhyay, Founder & CEO Esperer Onco Nutrition Pvt Ltd said “EON takes responsible nutrition very seriously and studies it with respect to the science of biochemistry. Our diet (D)impacting on infection status(I) which in turn influence nutrient depletion(N) and hence weakening the body immunity system (I),the whole chain goes unnoticed (till the disease state is asymptomatic) , lead to NCDs. This DINI Axis hypothesis we are intended to establish in our research plan to integrate responsible nutrition and NCDs like cancer ,diabetes etc .
Humans by nature have an inherent preference for palatable, sugary, salty, fatty and refined foods. These foods are mostly energy-dense and low in micro nutrients. Food production, processing, manufacturing, marketing and promotion have responded to these preferences by making high energy-dense foods available at increasingly affordable prices. This has led to changes in food consumption patterns which unfortunately coincided with more sedentary, less active lifestyles.
“The resultant over nutrition of especially macro nutrients is the major cause of obesity and also, together with obesity, a risk factor for many of the noncommunicable disease (NCDs) such as type 2 diabetes, coronary heart disease, stroke, hypertension, dental disease, osteoporosis, and some forms of cancer” Mr Chattopadhyay added.
The DINI AXIS research initiative is categorised into four steps, the first being the ecological meta-analysis which compares different populations and the effects of migration of populations on food availability during economic development and differences in dietary and nutrient intakes.
At the second stage scientist looked at numerous epidemiological/pandemic studies that have triggered the association between diet and biological risk factors of NCDs.
During the third, they studied the interventions between specific nutrients and foods in placebo-controlled trials using both healthy and diseased subjects to confirm the relationships of drug-nutrient interactions and its outcomes.
The fourth step followed molecular and genetic intervention under taken in research projects understanding how diet and nutrients affect genetic mutation and expression, adding to their knowledge of how nutrition influences immunity and improves quality of life.